On-line Hemodiafiltration
Prof (Dr) Debabrata Mukherjee | Senior Director – Nephrology
Medanta – The Medicity, Sector 38, Gurugram
Online Hemodiafiltration (HDF)
Online Hemodiafiltration (HDF) is a revolutionary dialysis modality that combines the benefits of both diffusion and convection to remove toxins from the blood.
Unlike conventional hemodialysis, HDF eliminates medium and larger molecules, such as beta-2 microglobulin, significantly improving outcomes for patients at Medanta Gurugram.
How is it Different from Conventional Dialysis?
| Feature | Conventional Dialysis | Online Hemodiafiltration (HDF) |
|---|---|---|
| Mechanism | Diffusion only | Diffusion + Convection |
| Toxin Clearance | Small molecules | Small & medium molecules |
| Water Quality | Standard | Ultrapure (Injection-grade) |
| Hypotension | Frequent | Rare (Highly Stable) |
Patient Success Story: Mr. Sharma’s Journey
“Mr. Sharma, a 64-year-old diabetic from Delhi, suffered from chronic fatigue and poor appetite. After shifting to **Online HDF at Medanta** under Dr. Mukherjee’s care, his quality of life dramatically improved. Within three months, his hypotension episodes stopped, and his phosphorus levels normalized. Today, he leads a healthier, more energetic life.”
Benefits of Online HDF
- Superior clearance of beta-2 microglobulin
- Fewer cardiovascular complications
- Reduced dialysis-related amyloidosis
- Improved control of anemia
- Better nutritional status
- Reduced intense itching (Pruritus)
Prof (Dr) D Mukherjee is an alumnus of the prestigious Armed Forces Medical College, Pune where he did his MBBS & MD (Medicine). Subsequently he went on to do his DM (Nephrology) from PGIMER Chandigarh, which is the foremost training institution for nephrology in India.