Polycystic Kidney Disease (PKD) Treatment
Best Nephrologist at Medanta

Polycystic Kidney Disease (PKD)

Polycystic Kidney Disease (PKD) is a hereditary condition where fluid-filled cysts grow in the kidneys, leading to enlargement and potential renal failure.
Prof (Dr) Debabrata Mukherjee at Medanta Medicity provides advanced management, from genetic counseling to Tolvaptan therapy.

Consultation Support:
+91 95994 71244

Types of PKD

1. Autosomal Dominant PKD (ADPKD)

  • Most common form, affecting 1 in 400–1,000 live births.
  • Mutations in PKD1 (85%) or PKD2 (15%).
  • Symptoms usually start appearing between ages 30–50.

2. Autosomal Recessive PKD (ARPKD)

  • Rare form, typically affecting 1 in 20,000 children.
  • Caused by PKHD1 gene mutation.
  • Often presents at birth or during early infancy with respiratory issues.

Consult the Expert

Get a personalized PKD management plan from the Best Nephrologist at Medanta Medicity.

Call Coordinator:
+91 95994 71244

Email:
dirnephro@gmail.com

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Symptoms to Watch For

ADPKD Symptoms

  • Flank or back pain
  • High blood pressure
  • Blood in urine (Hematuria)
  • Kidney stones

ARPKD Symptoms

  • Severely enlarged kidneys
  • Liver complications
  • Respiratory distress
  • Low amniotic fluid (Potter Sequence)

Advanced Diagnosis at Medanta

Using state-of-the-art imaging, Dr. Mukherjee ensures precise staging of PKD:

  • Ultrasound: Primary screening for cyst detection.
  • MRI/CT Scan: To measure Total Kidney Volume (TKV) for prognosis.
  • Genetic Testing: Screening for PKD1, PKD2, or PKHD1 mutations.

Treatment & Management

Tolvaptan Therapy

One of the major breakthroughs in PKD treatment. This therapy is approved for ADPKD to slow cyst growth and preserve kidney function for a longer period.

Supportive Care

Strict blood pressure control (ACE inhibitors), low-sodium diet, and high fluid intake are essential to slow progression.

ESRD Management

For advanced PKD, Dr. Mukherjee specializes in Dialysis and Kidney Transplant, ensuring high success rates.

Treatments