Consequences of Mineral Bone Disease

Mineral Bone Disease (MBD), often seen in chronic kidney disease (CKD), is a major concern. As Delhi’s leading nephrologist, Dr. Debabrata Mukherjee offers expert care for managing CKD-MBD and related conditions.

Common Consequences of CKD-MBD

• Bone abnormalities: Includes osteoporosis, osteopenia, and osteomalacia—causing fragile bones prone to fractures.
• Bone pain: Chronic bone pain reduces the patient’s quality of life.
• Fractures: Decreased bone density increases fracture risk even with minor trauma.
• Vascular calcification: Calcium deposits in blood vessels raise the risk of heart disease and stroke.
• Muscle weakness: Mineral imbalance affects mobility and increases fall risk.
• Secondary hyperparathyroidism: Elevated parathyroid hormone (PTH) levels worsen bone loss and vascular damage.
• Renal osteodystrophy: A CKD-specific bone disorder resulting from disrupted mineral metabolism.
• Pruritus: Chronic itchiness due to elevated blood calcium and phosphorus levels.
• Increased mortality: Cardiovascular complications and fractures increase death risk in CKD patients.
• Reduced quality of life: Physical discomfort, pain, and psychological distress are common.

Effective Management of Mineral Bone Disease

Dr. Debabrata Mukherjee recommends a multi-pronged approach: managing mineral imbalances, prescribing bone-health medications, monitoring kidney function, and guiding lifestyle modifications.