The most common causes of kidney disease include:
Diabetes: High blood sugar can damage kidney blood vessels over time.
High blood pressure (Hypertension): Increased blood pressure can damage kidney tissues.
Glomerulonephritis: Inflammation of the kidney's filtering units.
Polycystic Kidney Disease (PKD): A genetic disorder that causes cysts to form in the kidneys.
Kidney Stones: Hard deposits that form in the kidneys and can obstruct the urinary tract.
Urinary Tract Infections (UTIs): Frequent or untreated infections can affect kidney health.
Autoimmune Disorders: Diseases like lupus can cause kidney inflammation.
Symptoms of kidney disease may vary depending on the type and stage of the disease. Common symptoms include:
Swelling in the legs, ankles, or feet.
Fatigue or weakness.
Decreased urine output.
Dark, foamy, or blood-tinged urine.
Shortness of breath.
Nausea or vomiting.
Pain or discomfort in the back or sides (flank pain).
High blood pressure.
In the early stages, kidney disease may not cause noticeable symptoms, which is why regular check-ups are important.
Kidney disease is typically diagnosed using a combination of the following:
Blood Tests: To check kidney function, including tests for serum creatinine, glomerular filtration rate (GFR), and blood urea nitrogen (BUN).
Urine Tests: To detect proteins, blood, or other abnormalities in the urine.
Imaging Tests: Such as ultrasound or CT scans to visualize kidney structure and identify issues like kidney stones or cysts.
Kidney Biopsy: In some cases, a small tissue sample from the kidney may be taken to examine it for signs of damage or disease.
Chronic Kidney Disease (CKD) is a long-term condition where the kidneys gradually lose their ability to filter waste and excess fluids from the blood. Over time, CKD can lead to kidney failure, where the kidneys can no longer function adequately. Common causes of CKD include diabetes, high blood pressure, and glomerulonephritis. Early detection and treatment can help slow its progression.
CKD is classified into five stages based on the level of kidney function:
Stage 1: Mild kidney damage with normal GFR (90+ mL/min).
Stage 2: Mild reduction in kidney function (60–89 mL/min).
Stage 3: Moderate kidney damage (30–59 mL/min).
Stage 4: Severe reduction in kidney function (15–29 mL/min).
Stage 5: Kidney failure (GFR <15 mL/min), requiring dialysis or a kidney transplant.
Dialysis is a treatment that helps perform the functions of the kidneys when they are no longer able to do so effectively. There are two types of dialysis:
Hemodialysis: Blood is filtered outside the body through a machine.
Peritoneal Dialysis: The lining of the abdomen is used to filter waste from the blood, with a special fluid that is introduced and drained.
Dialysis is typically used in advanced stages of kidney failure (Stage 5 CKD) when the kidneys cannot filter waste on their own.
A kidney transplant is a surgical procedure where a healthy kidney from a donor is placed into the body of a person with kidney failure. The transplanted kidney takes over the function of the damaged kidneys. Transplants can come from living or deceased donors, and patients must take immunosuppressive drugs to prevent rejection of the new kidney.
To prevent kidney disease or reduce the risk of complications, consider the following:
Control blood sugar: If you have diabetes, keep your blood sugar levels under control.
Monitor blood pressure: Keep your blood pressure within the healthy range (typically below 120/80 mmHg).
Stay hydrated: Drink plenty of water to support kidney function.
Avoid excessive use of over-the-counter pain relievers: Medications like ibuprofen can damage the kidneys if used long-term.
Eat a healthy diet: Focus on a balanced diet low in salt, processed foods, and high-fat foods.
Regular exercise: Maintaining a healthy weight and staying active can help reduce the risk of kidney disease.
Diet plays a crucial role in managing kidney disease. Depending on the stage and type of kidney disease, dietary recommendations may include:
Reducing sodium to manage high blood pressure.
Limiting protein intake to reduce the workload on the kidneys.
Controlling potassium and phosphorus levels to prevent imbalances.
Managing fluid intake to prevent swelling in cases of kidney failure.
Consult with a dietitian specializing in kidney health to create a meal plan tailored to your needs.
Currently, there is no cure for chronic kidney disease, but it can be managed with proper treatment. Early-stage kidney disease can often be controlled through medication, lifestyle changes, and regular monitoring. In cases of kidney failure, treatment options such as dialysis or a kidney transplant are available.
Some kidney diseases, like Polycystic Kidney Disease (PKD), are inherited and passed down through families. If you have a family history of kidney disease, it’s important to discuss your risk with a healthcare provider and undergo regular kidney function tests.
Yes, untreated kidney disease can lead to various complications, including:
Heart disease
High blood pressure
Anemia (low red blood cell count)
Bone disease
Electrolyte imbalances
Managing kidney disease early can reduce the risk of these complications.
Your doctor may prescribe medications to manage the underlying causes of kidney disease, such as:
Blood pressure medications (e.g., ACE inhibitors, ARBs) to protect the kidneys.
Diuretics to help control fluid buildup.
Phosphate binders to control phosphorus levels.
Erythropoiesis-stimulating agents (ESAs) to treat anemia caused by kidney disease.
Always follow your Nephrologist's recommendations and attend regular check-ups.
Prof (Dr) D Mukherjee is an alumnus of the prestigious Armed Forces Medical College, Pune where he did his MBBS & MD (Medicine). Subsequently he went on to do his DM (Nephrology) from PGIMER Chandigarh, which is the foremost training institution for nephrology in India.