A Dialysis is an advanced form of hemodialysis, which is a treatment for individuals with kidney failure or end-stage kidney disease. This process involves using a machine to filter and cleanse the blood when the kidneys are no longer able to perform this function adequately. The blood is pumped through a dialyzer. It is also known as an artificial kidney which is used:

  • to remove waste products
  • excess fluids
  • electrolytes from the bloodstream.

    High-flux vs Low-Flux Dialyzers

    Earlier, low-flux dialyzes is often used. Low-flux dialyzers are effective in removing waste products but have limitations in removing larger molecules, such as certain middle-sized molecules and some inflammatory substances. High flux dialysis, on the other hand, utilizes a more permeable dialyzer membrane, allowing for enhanced clearance of larger molecules during the dialysis treatment.

    Advantages of high-flux dialysis

  • Improved Toxin Clearance:
  • High flux dialysis is more efficient in removing larger molecules like beta-2-microglobulin, which can accumulate in the body and contribute to long-term health complications.

    Reduced Risk of Complications:

    By better clearing toxins and waste products, high flux dialysis may potentially lead to a reduced risk of certain dialysis-related complications and conditions associated with kidney failure

    Better Nutrient Retention:

    High-flux dialysis can preserve essential nutrients and proteins more effectively than low-flux dialysis, leading to improved nutritional status for the patient.

    Enhanced Removal of Inflammatory Substances:

    High flux dialysis is more capable of removing certain inflammatory substances, which may be beneficial for individuals with chronic inflammation related to kidney failure.

    The choice between high-flux and low-flux dialysis depends on individual patient needs, their medical condition.Our Specialist Dr. Debabrata Mukherjee, would recommend the right method as per the patient’s condition. As High-flux dialysis may not be suitable for everyone, and it requires careful monitoring and adjustments to ensure the best outcomes.

    Ultimately, the goal of high flux dialysis, like any form of dialysis

  • To help manage kidney failure
  • To improve the patient’s quality of life, and
  • To provide them with a bridge to a kidney transplant if they are eligible for one.
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